Intersections between Physical Activity, Obesity, and Cancer Risk
Symposium C18
DOI:
https://doi.org/10.14288/hfjc.v14i3.646Keywords:
Cancer, Obesity, Physical Activity, Survival, RiskAbstract
Purpose: The purpose of this symposium is to explore the relationships among physical activity, obesity and cancer risk and survival, with a particular emphasis on the role of physical activity in reducing future health risks among cancer survivors.
Description: Over the past three decades, it has become increasing clear that the risk of several cancers is associated with obesity and physical inactivity. This symposium will present updated observational epidemiological evidence on these associations. In addition to the risk of developing a first cancer, there is also evidence that physical activity can attenuate the risk of developing further cancers in addition to reducing the risk of premature mortality. Finally, intervention studies among cancer survivors are beginning to identify potential mechanisms between these observed associations.
Chair: Dr. Peter T. Katzmarzyk, Pennington Biomedical Research Center, Baton Rouge, LA
Presenter 1: Dr. Peter T. Katzmarzyk, PhD, FACSM, FAHA, FTOS, Pennington Biomedical Research Center, Baton Rouge, LA. Title: Physical Activity, Obesity and Cancer Risk: Epidemiological Evidence
Presenter 2: Dr. Christine Friedenreich, PhD, FCAHS, FRSC, Alberta Health Services and Cumming School of Medicine and Faculty of Kinesiology, University of Calgary, Calgary, AB. Title: Role of Physical Activity and Weight Management in Promoting Health in Cancer Survivors
Presenter 3: Dr. Justin Brown, PhD, Pennington Biomedical Research Center, Baton Rouge, LA. Title: Testing Novel Physical Activity Intervention Strategies in Cancer Survivors: Understanding the Mechanisms
Results: Obesity is a significant risk factor for 13 cancers. The 2018 US Physical Activity Guidelines Advisory Committee found strong evidence that physical inactivity is associated with an increased risk of 7 cancers (bladder, breast, colon, endometrium, esophagus, gastric, and kidney), moderate evidence for 1 cancer (lung), and limited evidence for 7 cancers (hematologic, head and neck, ovary, pancreas, prostate, thyroid and rectal). Six of the 7 cancers with strong evidence of association with physical inactivity are obesity- related cancers. Furthermore, physical activity before and after diagnosis of a cancer is associated with improved survival for those diagnosed with breast and colon cancer. Intervention studies among cancer survivors have identified several potential underlying mechanisms that can be exploited to maximize personalized physical activity and obesity reduction therapies for cancer survivors.
Conclusions: This symposium addresses several issues related to the congress themes, including epidemiology, behaviour change, and clinical populations. The results will be widely applicable to clinical and public health settings around the world.
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Copyright (c) 2021 Peter Katzmarzyk, Christine Friedenreich, Justin Brown
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