TY - JOUR AU - Rostami, Saeid AU - Shephard, Roy J. AU - Rajaeian, Bijan PY - 2016/04/14 Y2 - 2024/03/29 TI - Effect of combined resistive-endurance exercises on myocardial tissue creatine kinase isoenzyme (CK-MB), IL-6 and IL-10 in male patients following cardiac surgery JF - The Health & Fitness Journal of Canada JA - Health Fit J Can VL - 8 IS - 2 SE - ARTICLES DO - 10.14288/hfjc.v8i2.186 UR - https://hfjc.library.ubc.ca/index.php/HFJC/article/view/186 SP - 3-12 AB - <em>Objectives</em>: The aims of the present study were to investigate the effects of concurrent endurance and resistance training upon the healing of cardiac patients following surgery as seen in plasma CK-MB, IL-6 and IL-10 concentrations. <em>Methods:</em> The experimental subjects were 63 males who had undergone a coronary bypass, balloon angioplasty or valve replacement. Control subjects were 35 men who had received a similar range of treatments, but were unwilling to enter the rehabilitation program. <em>Results:</em> Baseline anthropometric data, ventricular dimensions, ejection fraction and treadmill testing showed good initial matching of clinical status. The experimental group performed a one-hour exercise program 3 times per week for 8 weeks. After training, anthropometric measurements showed a decrease of body fat, and peak aerobic power and 6-minute walking distance showed expected gains.  The rehabilitation program led to substantial decreases in CK-MB, IL-6, and IL-10 in the experimental group. The decreases of IL-6 and IL-10 seen in experimental subjects appear to be independent of body fat loss and cardiac healing. <em>Conclusions:</em> A combined endurance-resistance training program not only improves physical condition following cardiac revascularization, but also speeds tissue healing relative to individuals of similar initial condition who have declined the option of exercise rehabilitation. ER -